Science
Pipeline
Committed to developing best-in-class programs for metabolic and cardiovascular disease
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Committed to developing best-in-class programs for metabolic and cardiovascular disease
Our pipeline consists of candidates that address a wide range of diseases including diabetes, heart failure, kidney disease, and NASH.
Type 1 diabetes mellitus (T1DM) is characterized by deficient insulin production, requiring daily or weekly administration of insulin to manage blood glucose levels. According to the Type 1 Diabetes Index, 8.7 million people are living with T1DM around the world.
Heart Failure (HF) is a clinical syndrome characterized by the impairment of the heart to circulate blood to different parts of the body. The prevalence of HF is about 1-3% of the general adult population, estimated to affect more than 64 million people worldwide. HF is a leading cause of hospitalization and cardiovascular death.
Chronic Kidney Disease (CKD) is a progressive condition leading to eventual loss of kidney function. Epidemiology studies estimate that more than 10% of the general population, or greater than 800 million people worldwide, have CKD. It is one of the leading causes of mortality and carries significant economic burden on individuals and the healthcare system.